Comparison of Neutralizing Antibody Titers Elicited by mRNA and Adenoviral Vector Vaccine against SARS-CoV-2 Variants | bioRxiv

Comparison of Neutralizing Antibody Titers Elicited by mRNA and Adenoviral Vector Vaccine against SARS-CoV-2 Variants | bioRxiv: The increasing prevalence of SARS-CoV-2 variants has raised concerns regarding possible decreases in vaccine efficacy. Here, neutralizing antibody titers elicited by mRNA-based and an adenoviral vector-based vaccine against variant pseudotyped viruses were compared. BNT162b2 and mRNA-1273-elicited antibodies showed modest neutralization resistance against Beta, Delta, Delta plus and Lambda variants whereas Ad26.COV2.S-elicited antibodies from a significant fraction of vaccinated individuals were of low neutralizing titer (IC50 <50). The data underscore the importance of surveillance for breakthrough infections that result in severe COVID-19 and suggest the benefit of a second immunization following Ad26.COV2.S to increase protection against the variants. ### Competing Interest Statement The authors have declared no competing interest.

Comments

Post a Comment

Popular posts from this blog

Dams, taps running dry in northern Mexico amid historic water shortages | Nasdaq

Dams, taps running dry in northern Mexico amid historic water shortages | Nasdaq : Her elderly neighbor is hard of hearing so Maria Luisa Robles, a convenience store worker in the northern Mexican city of Monterrey, shouted the question a second time: Have you run out of water? Human beings have the means, methods, and opportunities to help their fellow human regarding water. They just need to care enough to do it.
Read more

The conflict in Gaza: a view from Israel - The Lancet

The conflict in Gaza: a view from Israel - The Lancet : Khamis Elessi1 writes as a physician describing the deteriorating situation in the Gaza Strip (or Gaza) and pleads to save the residents of Gaza from catastrophe. We share his concern for all the innocent people in Israel and in Gaza. Unfortunately, his Correspondence contains inaccuracies and omits information that paints a very different picture of the catastrophe and its causes.
Read more